How to get from Des Moines to Charlotte: connecting flights, about 6h 32m total

Flights from Des Moines to Charlotte

Pick a departure date to see flights and seller prices

We search agencies and airlines for your day: nonstop and connecting flights, baggage, departure and arrival times.

Best fares from Des Moines to Charlotte

Lowest one-way prices found by recent searches for the next 120 days; press a card to search that date

Cheapest one-way $129 15 November 2026, nonstop Cheapest nonstop $129 15 November 2026, AA Cheapest in the next 7 days $129 15 November, Sun Cheapest weekend departure $143 Sat, 14 November 2026 Cheapest month November 2026 tickets from $129

Where to connect

Options with one connection, fastest first

fastest, via Atlanta: 6h 32m
two tickets, via Chicago: $208
connection options: 3
straight-line distance: 818 mi (1,317 km)

fastest

Via Atlanta

6h 32m

with the connection

Des Moines to Atlanta flight 2h 9m

Connection of about 3h

Atlanta to Charlotte flight 1h 23m

two ticketsfrom $699

Via Chicago

6h 46m

with the connection

Des Moines to Chicago flight 1h 40m

Connection of about 3h

Chicago to Charlotte flight 2h 6m

two ticketsfrom $208

Via Washington

7h 14m

with the connection

Des Moines to Washington flight 2h 35m

Connection of about 3h Arrival: Ronald Reagan National. Departure to Charlotte: Baltimore/Wash International Thurgood Marshall, Ronald Reagan National, Washington Dulles International.

Washington to Charlotte flight 1h 39m

One ticket or two

How the options are calculated and what to keep in mind at the connection

Flight times come from the nonstop schedule (estimated from the distance where there is no schedule), with 3h allowed for the connection. The price of an option is the sum of the lowest known fares for each leg; their dates may not match, so treat it as a guide. The search shows tickets for your dates, including connections on a single ticket.

Nearest nonstop flights

The closest you can get without a connection

From Des Moines to cities closest to Charlotte

Des Moines to Atlanta Atlanta: 226 mi (364 km) from Charlotte, flight 2h 9m from $261 Des Moines to Washington Washington: 329 mi (529 km) from Charlotte, flight 2h 35m Des Moines to Tampa Tampa: 512 mi (824 km) from Charlotte, flight 2h 43m Des Moines to New York New York: 531 mi (855 km) from Charlotte, flight 2h 38m from $98 Des Moines to Chicago Chicago: 587 mi (945 km) from Charlotte, flight 1h 40m from $108 Des Moines to Miami Miami: 655 mi (1,054 km) from Charlotte, flight 3h 11m

To Charlotte from cities closest to Des Moines

Minneapolis to Charlotte Minneapolis: 235 mi (378 km) from Des Moines, flight 2h 38m from $141 Springfield to Charlotte Springfield: 303 mi (488 km) from Des Moines, flight 2h 15m Milwaukee to Charlotte Milwaukee: 309 mi (497 km) from Des Moines, flight 2h 12m Chicago to Charlotte Chicago: 309 mi (498 km) from Des Moines, flight 2h 6m from $114 Indianapolis to Charlotte Indianapolis: 411 mi (661 km) from Des Moines, flight 1h 47m from $77 Fort Wayne to Charlotte Fort Wayne: 441 mi (710 km) from Des Moines, flight 2h 3m from $80

Frequently asked questions

Is there a nonstop flight from Des Moines to Charlotte?

There are no nonstop flights in the schedule. You will need a connection, the fastest is via Atlanta.

What is the fastest way to fly from Des Moines to Charlotte?

Via Atlanta: 2h 9m to the connection, 1h 23m after it, about 6h 32m in total with 3h for the connection.

How much does a flight from Des Moines to Charlotte with a connection cost?

Two nonstop tickets via Chicago from $208. This is the sum of the lowest known prices for each leg, and their dates may not match.

Which cities can you connect in between Des Moines and Charlotte?

Atlanta (6h 32m total), Chicago (6h 46m total) and Washington (7h 14m total).

How far is Charlotte from Des Moines?

818 mi (1,317 km) in a straight line between the cities.

How much time should I allow for the connection?

The options allow 3h. On a single ticket the carrier is responsible for the connection; on separate tickets you set the margin yourself, allowing time to collect and re-check your bags.