How to get from Syracuse to St Louis: connecting flights, about 7h 7m total

Flights from Syracuse to St Louis

Pick a departure date to see flights and seller prices

We search agencies and airlines for your day: nonstop and connecting flights, baggage, departure and arrival times.

Best fares from Syracuse to St Louis

Lowest one-way prices found by recent searches for the next 120 days; press a card to search that date

Cheapest one-way $306 19 November 2026, with a connection Cheapest month November 2026 tickets from $306

Where to connect

Options with one connection, fastest first

fastest, via Washington: 7h 7m
two tickets, via Boston: $254
connection options: 4
straight-line distance: 794 mi (1,278 km)

fastest

Via Washington

7h 7m

with the connection

Syracuse to Washington flight 1h 37m

Connection of about 3h Arrival: Ronald Reagan National, Washington Dulles International. Departure to St Louis: Baltimore/Wash International Thurgood Marshall, Ronald Reagan National, Washington Dulles International.

Washington to St Louis flight 2h 30m

Via New York

7h 19m

with the connection

Syracuse to New York flight 1h 24m

Connection of about 3h Arrival: John F. Kennedy International, LaGuardia. Departure to St Louis: LaGuardia, Newark Liberty International.

New York to St Louis flight 2h 55m

two ticketsfrom $344

Via Atlanta

7h 20m

with the connection

Syracuse to Atlanta flight 2h 35m

Connection of about 3h

Atlanta to St Louis flight 1h 45m

Via Boston

7h 35m

with the connection

Syracuse to Boston flight 1h 25m

Connection of about 3h

Boston to St Louis flight 3h 10m

two ticketsfrom $254

One ticket or two

How the options are calculated and what to keep in mind at the connection

Flight times come from the nonstop schedule (estimated from the distance where there is no schedule), with 3h allowed for the connection. The price of an option is the sum of the lowest known fares for each leg; their dates may not match, so treat it as a guide. The search shows tickets for your dates, including connections on a single ticket.

Nearest nonstop flights

The closest you can get without a connection

From Syracuse to cities closest to St Louis

Syracuse to Atlanta Atlanta: 467 mi (752 km) from St Louis, flight 2h 35m Syracuse to Charlotte Charlotte: 567 mi (913 km) from St Louis, flight 2h 17m Syracuse to Washington Washington: 709 mi (1,141 km) from St Louis, flight 1h 37m from $103 Syracuse to Orlando Orlando: 861 mi (1,386 km) from St Louis, flight 2h 59m from $139 Syracuse to Tampa Tampa: 862 mi (1,387 km) from St Louis, flight 3h Syracuse to New York New York: 872 mi (1,403 km) from St Louis, flight 1h 24m from $164

To St Louis from cities closest to Syracuse

Toronto to St Louis Toronto: 168 mi (270 km) from Syracuse, flight 2h 13m New York to St Louis New York: 195 mi (314 km) from Syracuse, flight 2h 55m from $141 Philadelphia to St Louis Philadelphia: 220 mi (354 km) from Syracuse, flight 2h 36m from $320 Boston to St Louis Boston: 263 mi (423 km) from Syracuse, flight 3h 10m from $173 Pittsburgh to St Louis Pittsburgh: 268 mi (431 km) from Syracuse, flight 1h 50m from $141 Washington to St Louis Washington: 291 mi (468 km) from Syracuse, flight 2h 30m

Frequently asked questions

Is there a nonstop flight from Syracuse to St Louis?

There are no nonstop flights in the schedule. You will need a connection, the fastest is via Washington.

What is the fastest way to fly from Syracuse to St Louis?

Via Washington: 1h 37m to the connection, 2h 30m after it, about 7h 7m in total with 3h for the connection.

How much does a flight from Syracuse to St Louis with a connection cost?

Two nonstop tickets via Boston from $254. This is the sum of the lowest known prices for each leg, and their dates may not match.

Which cities can you connect in between Syracuse and St Louis?

Washington (7h 7m total), New York (7h 19m total), Atlanta (7h 20m total) and Boston (7h 35m total).

How far is St Louis from Syracuse?

794 mi (1,278 km) in a straight line between the cities.

How much time should I allow for the connection?

The options allow 3h. On a single ticket the carrier is responsible for the connection; on separate tickets you set the margin yourself, allowing time to collect and re-check your bags.