Flights from St Louis to Key West
Pick a departure date to see flights and seller prices
We search agencies and airlines for your day: nonstop and connecting flights, baggage, departure and arrival times.
Where to connect
Options with one connection, fastest first
- fastest, via Tampa
- 6h 24m
- two tickets, via Miami
- $222
- connection options
- 4
- straight-line distance
- 1,090 mi (1,754 km)
fastest
Via Tampa
6h 24m
with the connection
St Louis to Tampa
flight 2h 20m
Connection of about 3h
Arrival: Tampa International. Departure to Key West: St. Petersburg-Clearwater International, Tampa International.
Tampa to Key West
flight 1h 4m
Via Miami
6h 43m
with the connection
St Louis to Miami
flight 2h 40m
Connection of about 3h
Arrival: Fort Lauderdale-Hollywood International, Miami International. Departure to Key West: Miami International.
Miami to Key West
flight 1h 3m
two ticketsfrom $222
Via Chicago
7h 57m
with the connection
Via Washington
8h 19m
with the connection
St Louis to Washington
flight 2h 3m
Connection of about 3h
Arrival: Baltimore/Wash International Thurgood Marshall, Ronald Reagan National, Washington Dulles International. Departure to Key West: Ronald Reagan National, Washington Dulles International.
Washington to Key West
flight 3h 16m
two ticketsfrom $532
One ticket or two
How the options are calculated and what to keep in mind at the connection
Flight times come from the nonstop schedule (estimated from the distance where there is no schedule), with 3h allowed for the connection. The price of an option is the sum of the lowest known fares for each leg; their dates may not match, so treat it as a guide. The search shows tickets for your dates, including connections on a single ticket.
Nearest nonstop flights
The closest you can get without a connection
From St Louis to cities closest to Key West
St Louis to Miami
Miami: 130 mi (209 km) from Key West, flight 2h 40m
from $117
St Louis to Fort Myers
Fort Myers: 144 mi (232 km) from Key West, flight 2h 25m
St Louis to Tampa
Tampa: 238 mi (383 km) from Key West, flight 2h 20m
St Louis to Cancun
Cancun: 399 mi (642 km) from Key West, flight 3h 15m
from $295
St Louis to New Orleans
New Orleans: 631 mi (1,015 km) from Key West, flight 1h 50m
St Louis to Atlanta
Atlanta: 654 mi (1,053 km) from Key West, flight 1h 33m
from $152
To Key West from cities closest to St Louis
Chicago to Key West
Chicago: 262 mi (422 km) from St Louis, flight 3h 29m
Washington to Key West
Washington: 709 mi (1,141 km) from St Louis, flight 3h 16m
from $100
Philadelphia to Key West
Philadelphia: 808 mi (1,301 km) from St Louis, flight 3h 22m
from $215
Orlando to Key West
Orlando: 861 mi (1,386 km) from St Louis, flight 1h 20m
from $41
Tampa to Key West
Tampa: 862 mi (1,387 km) from St Louis, flight 1h 4m
from $42
New York to Key West
New York: 872 mi (1,403 km) from St Louis, flight 3h 47m
from $238
Frequently asked questions
Is there a nonstop flight from St Louis to Key West?
There are no nonstop flights in the schedule. You will need a connection, the fastest is via Tampa.
What is the fastest way to fly from St Louis to Key West?
Via Tampa: 2h 20m to the connection, 1h 4m after it, about 6h 24m in total with 3h for the connection.
How much does a flight from St Louis to Key West with a connection cost?
Two nonstop tickets via Miami from $222. This is the sum of the lowest known prices for each leg, and their dates may not match.
Which cities can you connect in between St Louis and Key West?
Tampa (6h 24m total), Miami (6h 43m total), Chicago (7h 57m total) and Washington (8h 19m total).
How far is Key West from St Louis?
1,090 mi (1,754 km) in a straight line between the cities.
How much time should I allow for the connection?
The options allow 3h. On a single ticket the carrier is responsible for the connection; on separate tickets you set the margin yourself, allowing time to collect and re-check your bags.