How to get from St Louis to Buffalo: connecting flights, about 6h 8m total

Flights from St Louis to Buffalo

Pick a departure date to see flights and seller prices

We search agencies and airlines for your day: nonstop and connecting flights, baggage, departure and arrival times.

Where to connect

Options with one connection, fastest first

fastest, via Chicago: 6h 8m
two tickets, via Chicago: $152
connection options: 3
straight-line distance: 661 mi (1,063 km)

fastest

Via Chicago

6h 8m

with the connection

St Louis to Chicago flight 1h 28m

Connection of about 3h

Chicago to Buffalo flight 1h 40m

two ticketsfrom $152

Via Washington

6h 23m

with the connection

St Louis to Washington flight 2h 3m

Connection of about 3h Arrival: Baltimore/Wash International Thurgood Marshall, Ronald Reagan National, Washington Dulles International. Departure to Buffalo: Baltimore/Wash International Thurgood Marshall, Ronald Reagan National, Washington Dulles International.

Washington to Buffalo flight 1h 20m

two ticketsfrom $343

Via Philadelphia

6h 42m

with the connection

St Louis to Philadelphia flight 2h 11m

Connection of about 3h

Philadelphia to Buffalo flight 1h 31m

One ticket or two

How the options are calculated and what to keep in mind at the connection

Flight times come from the nonstop schedule (estimated from the distance where there is no schedule), with 3h allowed for the connection. The price of an option is the sum of the lowest known fares for each leg; their dates may not match, so treat it as a guide. The search shows tickets for your dates, including connections on a single ticket.

Nearest nonstop flights

The closest you can get without a connection

From St Louis to cities closest to Buffalo

St Louis to Toronto Toronto: 59 mi (95 km) from Buffalo, flight 1h 58m from $306 St Louis to Syracuse Syracuse: 139 mi (223 km) from Buffalo, flight 7h 20m St Louis to Cleveland Cleveland: 173 mi (279 km) from Buffalo, flight 1h 30m from $139 St Louis to Pittsburgh Pittsburgh: 178 mi (287 km) from Buffalo, flight 1h 35m St Louis to Detroit Detroit: 216 mi (347 km) from Buffalo, flight 1h 30m St Louis to Philadelphia Philadelphia: 280 mi (450 km) from Buffalo, flight 2h 11m from $187

To Buffalo from cities closest to St Louis

Chicago to Buffalo Chicago: 262 mi (422 km) from St Louis, flight 1h 40m from $165 Minneapolis to Buffalo Minneapolis: 467 mi (751 km) from St Louis, flight 2h 2m Atlanta to Buffalo Atlanta: 467 mi (752 km) from St Louis, flight 2h 5m from $140 Dallas to Buffalo Dallas: 548 mi (882 km) from St Louis, flight 2h 58m Charlotte to Buffalo Charlotte: 567 mi (913 km) from St Louis, flight 1h 46m New Orleans to Buffalo New Orleans: 600 mi (965 km) from St Louis, flight 4h 5m

Frequently asked questions

Is there a nonstop flight from St Louis to Buffalo?

There are no nonstop flights in the schedule. You will need a connection, the fastest is via Chicago.

What is the fastest way to fly from St Louis to Buffalo?

Via Chicago: 1h 28m to the connection, 1h 40m after it, about 6h 8m in total with 3h for the connection.

How much does a flight from St Louis to Buffalo with a connection cost?

Two nonstop tickets via Chicago from $152. This is the sum of the lowest known prices for each leg, and their dates may not match.

Which cities can you connect in between St Louis and Buffalo?

Chicago (6h 8m total), Washington (6h 23m total) and Philadelphia (6h 42m total).

How far is Buffalo from St Louis?

661 mi (1,063 km) in a straight line between the cities.

How much time should I allow for the connection?

The options allow 3h. On a single ticket the carrier is responsible for the connection; on separate tickets you set the margin yourself, allowing time to collect and re-check your bags.