How to get from Chicago to Knoxville: connecting flights, about 6h 7m total

Flights from Chicago to Knoxville

Pick a departure date to see flights and seller prices

We search agencies and airlines for your day: nonstop and connecting flights, baggage, departure and arrival times.

Prices by day: Chicago to Knoxville

Lowest one-way price in dollars from recent searches, cheap days in green. Press a day to see flights and exact prices.

Best fares from Chicago to Knoxville

Lowest one-way prices found by recent searches for the next 120 days; press a card to search that date

Cheapest one-way $81 13 November 2026, nonstop Cheapest nonstop $81 13 November 2026, G4 Cheapest in the next 7 days $81 13 November, Fri Cheapest weekend departure $81 Fri, 13 November 2026 Cheapest month November 2026 tickets from $81

Where to connect

Options with one connection, fastest first

fastest, via Atlanta: 6h 7m
two tickets, via Atlanta: $164
connection options: 2
straight-line distance: 455 mi (732 km)

fastest

Via Atlanta

6h 7m

with the connection

Chicago to Atlanta flight 2h 4m

Connection of about 3h

Atlanta to Knoxville flight 1h 3m

two ticketsfrom $164

Via Charlotte

6h 23m

with the connection

Chicago to Charlotte flight 2h 6m

Connection of about 3h

Charlotte to Knoxville flight 1h 17m

two ticketsfrom $206

One ticket or two

How the options are calculated and what to keep in mind at the connection

Flight times come from the nonstop schedule (estimated from the distance where there is no schedule), with 3h allowed for the connection. The price of an option is the sum of the lowest known fares for each leg; their dates may not match, so treat it as a guide. The search shows tickets for your dates, including connections on a single ticket.

Nearest nonstop flights

The closest you can get without a connection

From Chicago to cities closest to Knoxville

Chicago to Atlanta Atlanta: 155 mi (250 km) from Knoxville, flight 2h 4m from $57 Chicago to Nashville Nashville: 160 mi (258 km) from Knoxville, flight 1h 42m from $45 Chicago to Charlotte Charlotte: 180 mi (290 km) from Knoxville, flight 2h 6m from $114 Chicago to Louisville Louisville: 188 mi (302 km) from Knoxville, flight 1h 30m from $218 Chicago to Columbus Columbus: 281 mi (452 km) from Knoxville, flight 1h 31m from $92 Chicago to Lynchburg Lynchburg: 283 mi (456 km) from Knoxville, flight 2h 1m

To Knoxville from cities closest to Chicago

Charlotte to Knoxville Charlotte: 587 mi (945 km) from Chicago, flight 1h 17m from $92 Atlanta to Knoxville Atlanta: 589 mi (948 km) from Chicago, flight 1h 3m from $107 Washington to Knoxville Washington: 594 mi (956 km) from Chicago, flight 1h 49m from $83 New York to Knoxville New York: 711 mi (1,144 km) from Chicago, flight 2h 19m from $208 Dallas to Knoxville Dallas: 805 mi (1,295 km) from Chicago, flight 2h 6m from $143 Punta Gorda to Knoxville Punta Gorda: 1,082 mi (1,741 km) from Chicago, flight 1h 49m

Frequently asked questions

Is there a nonstop flight from Chicago to Knoxville?

There are no nonstop flights in the schedule. You will need a connection, the fastest is via Atlanta.

What is the fastest way to fly from Chicago to Knoxville?

Via Atlanta: 2h 4m to the connection, 1h 3m after it, about 6h 7m in total with 3h for the connection.

How much does a flight from Chicago to Knoxville with a connection cost?

Two nonstop tickets via Atlanta from $164. This is the sum of the lowest known prices for each leg, and their dates may not match.

Which cities can you connect in between Chicago and Knoxville?

Atlanta (6h 7m total) and Charlotte (6h 23m total).

How far is Knoxville from Chicago?

455 mi (732 km) in a straight line between the cities.

How much time should I allow for the connection?

The options allow 3h. On a single ticket the carrier is responsible for the connection; on separate tickets you set the margin yourself, allowing time to collect and re-check your bags.