How to get from Buffalo to St Louis: connecting flights, about 6h 5m total

Flights from Buffalo to St Louis

Pick a departure date to see flights and seller prices

We search agencies and airlines for your day: nonstop and connecting flights, baggage, departure and arrival times.

Where to connect

Options with one connection, fastest first

fastest, via Detroit: 6h 5m
two tickets, via Chicago: $150
connection options: 5
straight-line distance: 661 mi (1,063 km)

fastest

Via Detroit

6h 5m

with the connection

Buffalo to Detroit flight 1h 20m

Connection of about 3h

Detroit to St Louis flight 1h 45m

Via Nashville

6h 20m

with the connection

Buffalo to Nashville flight 2h 5m

Connection of about 3h

Nashville to St Louis flight 1h 15m

Via Chicago

6h 29m

with the connection

Buffalo to Chicago flight 2h 5m

Connection of about 3h

Chicago to St Louis flight 1h 24m

two ticketsfrom $150

Via Washington

6h 57m

with the connection

Buffalo to Washington flight 1h 27m

Connection of about 3h Arrival: Baltimore/Wash International Thurgood Marshall, Ronald Reagan National, Washington Dulles International. Departure to St Louis: Baltimore/Wash International Thurgood Marshall, Ronald Reagan National, Washington Dulles International.

Washington to St Louis flight 2h 30m

Via Philadelphia

7h 7m

with the connection

Buffalo to Philadelphia flight 1h 31m

Connection of about 3h

Philadelphia to St Louis flight 2h 36m

two ticketsfrom $491

One ticket or two

How the options are calculated and what to keep in mind at the connection

Flight times come from the nonstop schedule (estimated from the distance where there is no schedule), with 3h allowed for the connection. The price of an option is the sum of the lowest known fares for each leg; their dates may not match, so treat it as a guide. The search shows tickets for your dates, including connections on a single ticket.

Nearest nonstop flights

The closest you can get without a connection

From Buffalo to cities closest to St Louis

Buffalo to Nashville Nashville: 254 mi (408 km) from St Louis, flight 2h 5m Buffalo to Chicago Chicago: 262 mi (422 km) from St Louis, flight 2h 5m from $80 Buffalo to Detroit Detroit: 455 mi (732 km) from St Louis, flight 1h 20m Buffalo to Minneapolis Minneapolis: 467 mi (751 km) from St Louis, flight 2h 19m Buffalo to Atlanta Atlanta: 467 mi (752 km) from St Louis, flight 2h 19m Buffalo to Dallas Dallas: 548 mi (882 km) from St Louis, flight 3h 42m

To St Louis from cities closest to Buffalo

Toronto to St Louis Toronto: 59 mi (95 km) from Buffalo, flight 2h 13m Cleveland to St Louis Cleveland: 173 mi (279 km) from Buffalo, flight 1h 43m from $170 Pittsburgh to St Louis Pittsburgh: 178 mi (287 km) from Buffalo, flight 1h 50m Detroit to St Louis Detroit: 216 mi (347 km) from Buffalo, flight 1h 45m Philadelphia to St Louis Philadelphia: 280 mi (450 km) from Buffalo, flight 2h 36m from $320 Washington to St Louis Washington: 292 mi (470 km) from Buffalo, flight 2h 30m

Frequently asked questions

Is there a nonstop flight from Buffalo to St Louis?

There are no nonstop flights in the schedule. You will need a connection, the fastest is via Detroit.

What is the fastest way to fly from Buffalo to St Louis?

Via Detroit: 1h 20m to the connection, 1h 45m after it, about 6h 5m in total with 3h for the connection.

How much does a flight from Buffalo to St Louis with a connection cost?

Two nonstop tickets via Chicago from $150. This is the sum of the lowest known prices for each leg, and their dates may not match.

Which cities can you connect in between Buffalo and St Louis?

Detroit (6h 5m total), Nashville (6h 20m total), Chicago (6h 29m total), Washington (6h 57m total) and Philadelphia (7h 7m total).

How far is St Louis from Buffalo?

661 mi (1,063 km) in a straight line between the cities.

How much time should I allow for the connection?

The options allow 3h. On a single ticket the carrier is responsible for the connection; on separate tickets you set the margin yourself, allowing time to collect and re-check your bags.